THE 2001 BETHESDA SYSTEM

詳細はTHE BETHESDA SYSTEM WEBSITE ATLAS (http://rapids001.techriver.net/nih/index.php)

• SPECIMEN TYPE Indicate conventional  smear (Pap smear) vs. liquid-based preparation vs. other
• SPECIMEN  ADEQUACY
  • Satisfactory for  evaluation (describe presence or absence of endocervical/transformation  zone component and any other quality indicators, e.g., partially obscuring  blood, inflammation, etc)
  • Unsatisfactory for evaluation (specify reason)
    • Specimen rejected/not processed (specify reason)
    • Specimen processed and examined, but unsatisfactory for evaluation of epithelial      abnormality because of (specify reason)
• INTERPRETATION/RESULT
  • NEGATIVE FOR INTRAEPITHELIAL  LESION OR MALIGNANCY (when there is no cellular evidence of  neoplasia, state this in the General Categorization above and/or in the  Interpretation/Result section of the report, whether or not there are organisms  or other non-neoplastic findings)
    • Organisms
      • Trichomonas vaginalis
      • Fungal organisms morphologically  consistent with Candida spp
      • Shift in flora suggestive of  bacterial vaginosis
      • Bacteria morphologically  consistent with Actinomyces spp
      • Cellular changes consistent with  Herpes simplex virus
    • Other non-neoplastic  findings (Optional to report; list not inclusive)
      • Reactive cellular changes  associated with:
        • Inflammation (includes typical repair)
        • Radiation
        • Intrauterine contraceptive  device (IUD)
      • Glandular cells status post  hysterectomy
      • Atrophy
  • OTHER
    • Endometrial cells (in a woman >= 40 years of age)       (Specify if negative for squamous intraepithelial lesion・
  • EPITHELIAL CELL  ABNORMALITIES
    • Squamous cell
      • Atypical squamous cells
        • Of undetermined significance  (ASC-US)
        • Cannot exclude HSIL (ASC-H)
      • Low grade squamous intraepithelial lesion (LSIL) Encompassing: HPV/mild dysplasia/CIN 1
      • High grade squamous intraepithelial lesion (HSIL) Encompassing: moderate and severe  dysplasia, CIS; CIN 2 and CIN 3
        • With features suspicious for invasion (if invasion is suspected)
      • Squamous cell carcinoma
    • Glandular cell
      • Atypical
        • Endocervical cells, NOS or  specify in comments
        • Endometrial cells, NOS or  specify in comments
        • Glandular cells, NOS or specify  in comments
      • Atypical
        • Endocervical cells, favor  neoplastic
        • Glandular cells, favor  neoplastic
      • Endocervical adenocarcinoma in  situ
      • Adenocarcinoma
        • Endocervical
        • Endometrial
        • Extrauterine
        • Not otherwise specified  (NOS)
  • OTHER MALIGNANT NEOPLASMS (specify)
• ANCILLARY  TESTING
• AUTOMATED REVIEW
• EDUCATIONAL NOTES AND  SUGGESTIONS (optional)

執筆日：2005/08/23

執筆者：神戸大学病院病理部病理診断科　伊藤　智雄　　tomitoh@med.kobe-u.ac.jp