免疫組織データベース~いむーの



bcl-6

2015年3月4日

Recommended control tissue:Lymphoid tissues containing follicular centers.

Staining pattern: neulcei

bcl-6 is a a transcriptional repressor which is necessary for germinal center formation.

This antibody is react with normal germinal center B-cells. In malignant lymphomas, it is positive for those with germinal center differenrtiation, such as follicular lymphoma and Burkitt lymphoma etc.

 

image3 Fig: bcl-6 positive diffuse large B-cell lymphoma

 

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