Recommended positive controls: Tonsil, lymphoid tissues.
Staining pattern: membrane
Reactive to: NL cells, subpopulation of T-cells, plasma cells, neural cells, neuroendocrine cells.
1) Diagnosis of hematolymphoid neoplasms:
NK/T cell lymphoma, Some T-cell lymphomas, Plasmacytoma, Some analastic large cell lymphoma, Some myeloid leukemias.
2) Diagnosis of neural/neuroendocrine tumors.
Figure: Extranodal NK/T-cell lymphoma, nasal type.